To clean up Great Stuff Expanding foam, use Acetone to wipe any areas clean. If you're using a dispensing gun, then you can use GREAT STUFF PRO Dispensing Gun Cleaner. Keep in mind, if spray foam gets on your clothes, they may be ruined, so be sure to wear clothes you don't care about or get a protective suit, and gloves. You should also wear an air mask and goggles when using spray foam. You do not want to get expanding foam in your eyes, and breathing the fumes that eminate from spray foam can cause lung and throat irritation.