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What's the difference between Neosporin vs. Polysporin?

When should you use Neosporin vs. Polysporin on your skin?
Jan 13th, 2012


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Neosporin and Polysporin are two topical ointments that may seem interchangeable, however there is one key difference that separates the two. The main difference is the Neosporin ointment contains Neomycin, which is an aminoglycoside antibiotic found in many other topical medications such as creams, ointments, and eyedrops.

However, because Neomycin can cause allergic reactions in some individuals, dermotologists and many plastic surgeons do not want their patients using Neosporin, and instead recommend Polysporin to heal up cuts and scars. Note: many dermotologists will just recommend Bacitracin (with Zinc) since Bacitracin is least likely to cause any allergic reactions as compared to Polysporin and Neosporin.  But because Neosporin combines three antibiotics, instead of only two in Polysporin, you may treat or prevent a wider range of bacterial infections by using Neosporin.

See the differences between the two below.

Neosporin Original Active Ingredients:
- Polymyxin B Sulfate
- Bacitracin Zinc
- Neomycin

Polysporin Ointment Active Ingredients:
- Polymyxin B Sulfate
- Bacitracin Zinc



gail
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How would you know when to use polysporin or neosporin

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